12/3/2023 0 Comments Carla gonzalez vargas![]() Yee, D., Van Den Berg, C., Kozelsky, T.W., Kuhn, J.G., Cox, G.N.“Use of hydroxyurea to alter drug resistance of human tumor cells” In: Mugia FM, ed., Chemotherapy: concepts, mechanisms, and disease targets. Vancouver:Applied Therapeutics 1995:88-1-17. DNA sequence amplification in human prostate cancer identified by chromosome microdissection: Potential prognostic implications. Van Den Berg, C., Guan, X-Y, Von Hoff, D., Jenkins, R., Bittner, M., Griffin, C., Kallonemi, O., Visakorpi, T., McGill J., Hearth, J., Epstein, J., Sarosdy, M., Meltzer, P., Trent, J.A phase I and pharmacokinetics study of 2-chlorodeoxyadenosine in patients with solid cancers. Weiss, G.R., Kuhn, J.G., Rizzo, J., Smith, L.S., Rodriguez, G.I., Eckardt, J., Burris, H.A., III, Fields, S., Van Den Berg, K., Von Hoff, D.D.Pharmacokinetics of hydroxyurea in nude mice. Van Den Berg, C., McGill, J.R., Kuhn, J.G., Walsh, J.T., De La Cruz, P.S., Davidson, K.K., Wahl, G.M., Von Hoff, D.D.Ultimately, we hope to evaluate if JNK can be therapeutically targeted to treat breast cancer patients. Our current studies are aimed to better characterize how JNKs mediate these phenotypic responses. Using microarray technology we have identified several genes through which JNKs influence cellular response to growth factors. JNKs also affect mammary development by influencing mammary cell differentiation. We have found that in response to activation of RTKs, JNKs play critical roles in tumorigenesis, DNA damage, cell migration, and metastasis. ![]() To better understand their various functions, we study jnk1 and jnk2 in mammary gland development, mammary tumorigenesis/metastases, and response to chemotherapy treatment. However, our studies have shown that jnk1 and jnk2 gene products have diverse roles. Three jnk genes are expressed in eukaryotes and their products were initially thought to convey cell death signals. We focus on a group of proteins known as JNK (c-Jun N-terminal Kinases) which are activated by receptor tyrosine kinases in breast cancer models. RTKs including IGF-IR, EGFR, and Met, propagate tumor behavior by increasing cell proliferation, tumor cell movement (motility), tissue invasion, and metastasis. Receptor tyrosine kinases (RTKs) convey pro-tumorigenic responses in breast, colon, lung, and prostate cancer. | College of Pharmacy retweet icon bullhorn icon reply icon info icon flickr icon tumblr icon vimeo icon reddit icon podcast icon angle-down icon angle-left icon angle-right icon angle-up icon ban icon hamburger icon book icon bookmark icon bug icon caret-down icon caret-left icon caret-right icon caret-up icon chain icon check icon check-circle icon chevron-down icon chevron-left icon chevron-right icon chevron-up icon circle icon circle-o icon clone icon close icon download-cloud icon code icon download icon ellipsis icon envelope icon warning icon external-link icon eye icon eye-slash icon facebook icon github icon google-plus icon heart icon heart-o icon home icon info-circle icon instagram icon linkedin icon lock icon medium icon minus-circle icon send icon pause-circle icon play-circle icon plus-circle icon question-circle icon quote-left icon quote-right icon rss-square icon search icon share-alt icon slack icon snapchat icon ticket icon twitter icon wheelchair icon youtube icon Ivanna is currently part of the "Berklee Institute for Jazz and Gender Justice" directed by Terri Lyne Carrington.Carla Van Den Berg, Pharm.D. In 2017 she started her own group The Unity Ensemble. In addition, she has studied with Neal Smith, Terri Lyne Carrington, Francisco Mela, Tia Fuller, John Riley, among others. Ivanna has performed with artists such as Concha Buika (México Tour), Kris Davis (Dizzy's NY), Dee Dee Bridgewater, Cassandra Wilson, Leo Blanco, Jacques Schwarz-Bart (Martinica Tour), Nando Michelin Quartet, Tia Fuller, Luisito Quintero, Sócrates García Big Band, Jane Bunette and Maqueque (Canada Tour), and Sona Jobarteh. In 2019, she won first place in the "Hit like a Girl 2019" contest, where she then participated in PASIC 2019 in Indianapolis. In 2018, Ivanna started to be part of the Paiste Cymbals family. Ivanna has been part of important groups in the Dominican Republic such as Carijazz, Gustavo Rodríguez Trio, Javier Vargas and Atre, The Big Band of the Conservatory of Music directed by Javier Vargas, etc. Graduated from the DR Conservatory and currently from Berklee College of Music. Drummer and Composer born in Santo Domingo, Dominican Republic.
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